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Ribavirin can cause birth defects or death in an unborn baby. x��Xko����_1�"��el��&��`���E@��&k�$DҎ��3s_��(j�XI�}�;s��̽Y����Ɇ��3l� "��_,�IJ|�7|���.�ί68�~��s۲� � �9>�,�?��X�x��?9�q����~��]��gv=DžY��m^�q?��ܱaV6��K�3z����r`��90��AU�S����l���d�O��e��2�/�����?����x��]�?+��º*����*�vI�����y�q��3n�p���氀�;�����F�f�����p�/���wLK1���{�f�U����;��[������b�, Managing Side Effects of Epclusa (Sofosbuvir/Velpatasvir), Veterans Health Administration Patient Care Services. Get medical help right away if you take these medicines and you have: very slow heartbeats, chest pain, shortness of breath; weakness, extreme tiredness, light-headed feeling (like you might pass out). Epclusa is used to treat chronic hepatitis C in adults and children 6 years of age and older or weighing at least 17kg (37 lbs). -Dose recommendations also apply to HCV/HIV-1-coinfected patients. Stopping suddenly could make your hepatitis C harder to treat with antiviral medicine. Do not share your medicine with other people. In some clinical studies, 98%-100% of patients were cured after 12 weeks of Epclusa … -In patients without cirrhosis or with compensated cirrhosis You should not breast feed during treatment with EPCLUSA. Then take … Do not take more than 1 tablet of ® in a day. -In combination with ribavirin: In patients with decompensated cirrhosis. <> Potential for serious heart problems when Epclusa is taken with amiodarone. Tell your doctor about all your current medicines and any medicine you start or stop using. These medications may cause some risk when taken together. Uses: For the treatment of chronic HCV genotype 1, 2, 3, 4, 5, or 6 infection Comments: Do not take EPCLUSA after the expiry or “use by” date (EXP) printed on the bottle. This is why you must never take antacids when you are taking Epclusa or any other substance that might neutralise your stomach acid. The drugs in Epclusa have not been tested in pregnant or breastfeeding women, or in children and adolescents with hepatitis C. Epclusa has not yet been tested in people with advanced … It is not known whether this medicine will harm an unborn baby. endstream You will need frequent blood tests to check your liver function. Prices are for cash paying customers only and are not valid with insurance plans. Our Epclusa (sofosbuvir and velpatasvir) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Refer to the ribavirin prescribing information for a list of contraindications for ribavirin … This medicine is not a treatment for HIV or AIDS. -In clinical trials, therapy-experienced patients received a peginterferon alfa/ribavirin-based regimen with or without an HCV nonstructural protein 3/4A (NS3/4A) protease inhibitor (boceprevir, simeprevir, or telaprevir). You will take Epclusa® once daily by mouth with or without food. Epclusa does not require administration with interferons or ribavirin (Rebetol) except when used to treat patients with decompensated cirrhosis. • Take EPCLUSA with or without food. If you are a man, do not use ribavirin if your sexual partner is pregnant. If you forget to take Epclusa. -Weight 17 to less than 30 kg: Sofosbuvir 200 mg-velpatasvir 50 mg orally once a day Many say that they begin to feel markedly better approximately two weeks after they stop taking the medication(s). Do not change your dose or dosing schedule without your doctor's advice. If you have ever had hepatitis B, using sofosbuvir and velpatasvir can cause this virus to become active or get worse. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. When taking Epclusa with other medicine: To make sure all medicines are safe for you, tell your doctor about all your medical conditions, and if you are pregnant or breastfeeding. For some, this healing process is based solely on the effects of the medication(s). Patients should be instructed not to take a double dose of Epclusa. • Do not stop taking EPCLUSA without first talking with your healthcare provider. 1 Generic Name: sofosbuvir and velpatasvir (soe FOS bue vir and vel PAT as vir) Sometimes it is not safe to use certain medications at the same time. • … Use Epclusa (Sofosbuvir And Velpatasvir) exactly as directed on the label, or as prescribed by your doctor. Epclusa is usually taken once per day for 12 weeks. Epclusa is sometimes used in people who also have HIV. Do not take EPCLUSA after the expiry or “use by” date (EXP) printed on the bottle. Follow all directions on your prescription label and read all medication guides or instruction sheets. How to take Epclusa (Sofosbuvir And Velpatasvir)? Comments: Some think that their last treatment means they are done dealing with hepatitis C. This is not so. Do not take St. John’s Wort herbal supplements with Epclusa, and tell your doctor if you are taking medications for cancer, seizures, bacterial infections, heartburn/acid reflux, or statins. Epclusa … Using Epclusa will not prevent your disease from spreading. Many drugs can interact with sofosbuvir and velpatasvir. endobj -Dose recommendations also apply to HCV/HIV-1-coinfected patients. If you take it after the expiry date has passed, it may not … Usual Adult Dose for Chronic Hepatitis C: Sofosbuvir 400 mg-velpatasvir 100 mg orally once a day Use effective birth control to prevent pregnancy while using these medicines together and for at least 6 months after treatment ends. 1 0 obj This includes prescription and over-the-counter medicines, vitamins, and herbal products. Ask your doctor about any risk. You may need frequent liver function tests while using this medicine and for several months after you stop. You may report side effects to FDA at 1-800-FDA-1088. Call your doctor for medical advice about side effects. At the age of 30, my mother got her dentures. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using ribavirin. endobj It is important not to miss a dose of this medicine. If it is … Sharing drug or medicine needles is never safe, even for a healthy person. Get medical help right away if you take amiodarone with EPCLUSA and get any of the following symptoms: fainting or near-fainting, dizziness or lightheadedness, not feeling well, weakness, extreme tiredness, shortness of breath, chest pains, confusion, or memory problems. The prescribing information for Epclusa recommends that people not take Prilosec (omeprazole) or other proton-pump inhibitors (PPIs) unless medically necessary. Adult patients who have previously failed therapy with an NS5A-containing regimen. Store this medicine in the original container at room temperature away from moisture and heat. Use all medications as directed and read all medication guides you receive. If you also take a heart rhythm medicine called amiodarone: Taking amiodarone with sofosbuvir and velpatasvir can cause dangerous side effects on your heart. Last updated on Dec 1, 2020. This is not … The most common side effects of EPCLUSA include headache and tiredness. Epclusa treats specific genotypes of hepatitis C, and only in certain people. Do not use ribavirin if you are pregnant, or if you are a man and your sexual partner is pregnant. When you start or stop taking Epclusa, your doctor may need to adjust the doses of any other medicines you take on a regular basis. <>stream Epclusa contains a combination of sofosbuvir and velpatasvir. Every person with chronic hepatitis C should remain under the care of a doctor. I was lucky, I didn’t get mine until I was 50. <>stream It may not be safe to breastfeed while using this medicine. Not a large amount of food, not a huge meal, because some of the Velpatasvir is going to get caught up in the mass of food. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. If you take cimetidine, dexlansoprazole, esomeprazole, famotidine, lansoprazole, nizatidine, omeprazole, pantoprazole, rabeprazole, or ranitidine, ask your doctor or pharmacist … They mention that you may get dry mouth or a metallic taste but the never share the fact that this drug will rot your teeth. A generic version of Epclusa … If you have ever had hepatitis B, Epclusa can cause this condition to come back or get worse. If you miss a dose, take the missed dose as soon as you remember the same day. Store the medication at room temperature. Not … Version: 6.03. sofosbuvir, Vosevi, Sovaldi, Mavyret, Harvoni, ribavirin. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. -Therapy-naive and therapy-experienced, with decompensated cirrhosis (Child-Pugh B or C): Sofosbuvir-velpatasvir plus ribavirin for 12 weeks What is Epclusa? I have 2 teeth that serve as an anchor for my lower denture. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Get your prescription refilled before you run out of medicine completely. Take your next dose at your Epclusa … Even after the doctor has run all of the tests to indicate no further viral load, the body will still need time to heal. An unborn baby could be harmed if you have sex with a pregnant woman while you are taking ribavirin. You should not use Epclusa if you are allergic to sofosbuvir or velpatasvir. Epclusa is sometimes used in combination with ribavirin. Do not have unprotected sex or share razors or toothbrushes. Copyright 1996-2021 Cerner Multum, Inc. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. 3 0 obj • It is important that you do not miss or skip doses of EPCLUSA during treatment. Ribavirin use by either parent may cause birth defects. Epclusa is sometimes used in combination with ribavirin. Usual Pediatric Dose for Chronic Hepatitis C: 6 years or older: <>/ProcSet[/PDF/Text]/ColorSpace<>/Font<>>>/Tabs/S/MediaBox[0.0 0.0 612.0 792.0]/TrimBox[0.0 0.0 612.0 792.0]/BleedBox[0.0 0.0 612.0 792.0]/StructParents 1/Annots[]/ArtBox[0.0 0.0 612.0 792.0]/Rotate 0>> A serious slowing of the heart rate (symptomatic bradycardia) may occur when the drug amiodarone, which is used to treat an … Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If you are a woman, do not use ribavirin if you are pregnant. Tell your doctor if you are pregnant or plan to become pregnant. While taking Epclusa with ribavirin, use at least 2 effective forms of birth control to prevent pregnancy, whether you are a man or a woman. Veterans Health Administration Patient Care Services Brand Name: Epclusa. So what I read is take the Epclusa with food then wait 4 hours before taking omeprezole (Prilosec). When taking Epclusa with other medicine: To make sure all medicines are safe for you, tell your doctor about all your medical conditions, and if you are pregnant or breastfeeding. Talk with your doctor about safe ways to prevent HCV transmission during sex. -Therapy-naive and therapy-experienced, without cirrhosis and with compensated cirrhosis (Child-Pugh A): Sofosbuvir-velpatasvir for 12 weeks This is not a complete list of side effects and others may occur. It is sometimes given in combination with another antiviral medicine called ribavirin in people who also have advanced cirrhosis. 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